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Publications

Journal Publications

  1. Sharma, P., Sheets, K., Subbiah, E. & Nain, A. S. The mechanistic influence of aligned nanofiber networks on cell shape, migration and blebbing dynamics of glioma cells. Integr. Biol. 5, 1036-1044 (2013)

  2. Sheets, K., Wang, J., Meehan, S., Sharma, P., Ng, C., Khan, M., and Nain, A.S. 2013.  J. Biomat Tissue Eng. In Press.
  3. Sheets, K., Wunsch, S., Ng,C., Nain, A.S., Shape-Dependent Cell Migration and Focal Adhesion Organization on Suspended and Aligned Nanofiber Scaffolds, Acta Biomaterialia (2013), doi:http://dx.doi.org/10.1016/j.actbio.2013.03.042
  4. Wang, Ji, Junbo Hou, Michael W. Ellis, and Amrinder S. Nain. "Organized Long Titanium Dioxide Nanofibers/Nanotubes with Controlled Morphology Using Sol-Gel Combined STEP technique." New Journal of Chemistry. 37.3 (2013): 571-574. Web. 24 Apr. 2013. <http://dx.doi.org/10.1039/C2NJ40886D>.
  5. Nain, Amrinder S., and Ji Wang. "Polymeric Nanofibers: Isodiametric Design Space and Methodology for Depositing Aligned Nanofiber Arrays in Single and Multiple Layers." Nature, Polymer Journal. (2013): n. page. Web. 24 Apr. 2013. <http://www.nature.com/pj/journal/vaop/ncurrent/full/pj20131a.html>.
  6. Y. Yang, J. Wang, J. Li, D. Viehland and A. Nain, "Nanoparticles Deposition at Specific Sites Using Aligned Fiber Networks," Open Journal of Inorganic Non-metallic Materials, Vol. 2 No. 4, 2012, pp. 55-58. doi: 10.4236/ojinm.2012.24006.
  7. Kargar, Mehdi, Ji Wang, Amrinder Nain, and Bahareh Behkam. "Controlling bacterial adhesion to surfaces using topographical cues: a study of the interaction of Pseudomonas aeruginosa with nanofiber-textured surfaces." Soft Matter. 8.40 (2012): 10254-10259. Web. 9 Oct. 2012 . 
  8. Ker E., Nain A. S., Wang J., Amon C., and Campbell P., “Bioprinting of Growth Factors onto Sub-micron Fiber-Based Scaffolds for the Regeneration of Musculoskeletal Interfaces”, Biomaterials, 32( 32), 8097-8107, 2011.
  9. Bakhru, S, Nain, A. S., Campbell, P, Zappe, S, and Amon, C., “Direct and Cell Signaling-Based, Geometry-Induced Neuronal Differentiation of Neural Stem Cells”,”, Integrative Biology, In Print. 
  10. Nain A. S., Bakhru, S., Kellogg, R., Wang, J., Highley, C.,Campbell, P., Amon, C.,and Zappe,S.,"STEP-Aligned Polymer Fiber Meshes Direct Migration and Neuronal Differentiation of Neural Stem Cells", Under Review. 
  11. Nain A. S., Bowen, W., Campbell, P., Michalopoulos, G., and Amon,C.,"Sustainable Acrobatic Hepatocyte Monolayers on customized Biomaterial Micro/nanofibrous Scaffolds" Under Review. 
  12. Nain A. S., Sitti, M., Jacobson, A., Kowalewski, Campbell P., and Amon, C.,"Polymeric Nanofibers: Isodiameteric Design Space and Methodology for Depositing Aligned Nanofiber Arrays", Under Review. 
  13. Nain, A. S., Filiz S., Ozdogonlar, B., Sitti, M., and Amon, C.,“Aligned Deposition and Modal Characterization of Micron and Submicron Poly(Methyl Methacyrlate) Fiber Cantilevers”, Review of Scientific Instruments, Vol. 81(1), pp. 016102-1 to 3, 2010. 
  14. Nain A. S., Kowalewski, T., Jacobson, A., Sitti, M., and Amon, C.,"Dry Spinning based Spinneret based Tunable Engineered Parameters (STEP) Technique for Controlled and Aligned Deposition of Polymeric Nanofibers",Macromolecular Rapid Communications, 30, pp. 1406-1412, 2009. 
  15. Nain A. S., Phillippi J. A., Sitti, M., MacKrell, J., Campbell, P. G., and Amon, C.,"Control of Cell Behavior by Aligned Micro/Nanofibrous Biomaterial Scaffolds Fabricated by Spinneret-based Tunable Engineered Parameters (STEP) Technique", Small, 4(8), 1153-1159, 2008
  16. Nain, A. S., Amon, C., and Sitti, M.“Proximal Probes Based Nanorobotic Drawing of Polymer Micro/Nanofibers”, IEEE. Transactions of Nanotechnology, Vol. 5(5), pp499-510, 2006. 
  17. Nain, A. S., Wong, J. C., Amon, C., and Sitti, M.,“Drawing Suspended Polymer Micro/Nanofibers using Glass Micropipettes”, Applied Physics Letters, Vol. 89(18), pp. 183105-7, 2006. Selected for Virtual Journal of Nanoscale Science & Technology.

Conferences

  1. T. O’Brien, A. Nain, (poster), “The Application of Inverse Mathematics and Beam Theory to Determine Migratory Single Cell Forces” (Poster), Annual Meeting of Biomedical Engineering Society (BMES), Atlanta, Georgia, October 2012
  2. S. Bhatia, P. Sharma, A. Nain. “The Effect of Curcumin on Single-cell Glioma Force
    Generation” (Poster),
  3. C. Hughes, P. Sharma, A. Nain. Fused nanofiber scaffolds as force measurement probes for breast cancer cell lines (Poster), Annual Meeting of Biomedical Engineering Society (BMES), Atlanta, Georgia, October 2012
  4. C. Hughes, P. Sharma, A. Nain. Fused Nanofiber Scaffolds as Force Measurement Probes for Breast Cancer Cell Lines (Poster), Virginia Tech Summer Undergraduate Research Symposium, August 3 2012
  5. K. Sheets, A. Nain.  “Role of Aligned Polymer Fibers in Tissue Engineering” (Presentation), IUPAC World Polymer Congress, 2012
  6. K. Sheets, J. Wang, A. Nain.  “Polystyrene-Polyurethane Scaffolds as Force Measurement Probes for Single Cells” (Poster), IUPAC World Polymer Congress, 2012
  7. K. Sheets, A. Nain.  “Cell Shape Control and Related Focal Adhesion Dynamics on STEP Fibers” (Presentation), American Society of Mechanical Engineers (ASME), 2012
  8. P. Sharma*, K. Sheets*, A. Nain.  “Geometry Induced Cytoplasmic Bleb Dynamics and the Influence of Stiffness of STEP Polymeric Fibers on Glioblastoma Multiforme Cell Migration” (Presentation) (*equal contribution), American Society of Mechanical Engineers (ASME), 2012
  9. K. Sheets, A. Nain.  “Cytoskeleton Dynamics and Cell Shape Control with Aligned Nanofiber Scaffolds” (Poster), 11th Annual SBES Symposium, 2012
  10. B. Koons, A. Nain. “Cellular Behavior in a Tunable Mechanistic Environment” (Poster), 1st annual Interdisciplinary Research Symposium at Virginia Tech, 2011
  11. T. O’Brien, A, Nain. “PMMA Polymer System Development for Nanofiber Applications in Biomedical and Advanced Materials” (Poster), 1st annual Interdisciplinary Research Symposium at Virginia Tech, 2011
  12. K. Sheets, A. Nain.  “Control on Cell Migration Using a Mechanistically Tunable Fibrous Environment” (Presentation), Annual Meeting of the American Institute of Chemical Engineers (AIChE), 2011
  13. K. Sheets, A. Nain.  “Control on Glioblastoma Multiforme Dynamics Using Aligned Fiber Networks” (Presentation), Annual Meeting of the American Institute of Chemical Engineers (AIChE), 2011
  14. S. Wunsch, K. Sheets, A. Nain. “Cellular Dynamics on Aligned Fibrous Scaffolds of Tunable Stiffness” (Poster), Annual Meeting of Biomedical Engineering Society (BMES),2011
  15. K. Sheets, J. Wang, A. Nain. “Real-Time Monitoring of Cell Stretching and Migration on Aligned Fibrous Scaffolds” (Poster), Annual Meeting of Biomedical Engineering Society (BMES), 2011
  16. J. Wang, K. Sheets, A. Nain. “Highly Elastic and Aligned Polyurethane Fiber Scaffolds for Tissue Engineering” (Poster), Annual Meeting of Biomedical Engineering Society (BMES), 2011
  17. K. Sheets, A. Nain.  “Tunable Fibrous Microenvironment as a Platform for Studying Cellular Dynamics” (Poster), 10th Annual SBES Symposium, 2011
  18. K. Sheets, E. Subbiah, A. Nain.  “Dynamics of Cancer Cell Blebbing on Aligned Fibrous Networks” (Published Abstract), VT Cancer Symposium, 2011
  19. K. Sheets, A. Nain.  “Topological-Mechanistic Cues Direct Cellular Dynamics On Aligned Polymeric Step Scaffolds.” (Presentation), American Society of Mechanical Engineers (ASME), 2011
  20. S. Wunsch, and A. Nain, Cytoskeletal Arrangement of Cells Migrating in a 3D Fibrous Environment,  9th Annual Undergraduate Research and Prospective Graduate Student Conference, Virginia Tech, April 15th, 2011.
  21. J. Haught, and A. Nain, Nanofiber Braid Composite Materials for Advanced Materials,  9th Annual Undergraduate Research and Prospective Graduate Student Conference, Virginia Tech, April 15th, 2011
  22. C. Ng, A. Nain. Cellular Dynamics on Aligned Fibrous PLGA Scaffolds,  9th Annual Undergraduate Research and Prospective Graduate Student Conference, Virginia Tech, April 15th, 2011
  23. K. Sheets, A. Nain.  “Topological-Mechanistic Cues Direct Cellular Dynamics on Aligned Polymeric STEP Scaffolds” (Poster), Biophysical Society 55th Annual Meeting, 2010
  24. S. Wunsch, C. Ng, and A. Nain. Step Scaffolds for Tissue Engineering Application, BI04,  12th Annual Conference of the North Carolina Tissue Engineering and Regenerative Medicine Society, November 12, 2010 Research Triangle Park, North Carolina
  25. K. Sheets, A. Whittington.  “Mechanical and Cellular Response to Biomineralization of Ovalbumin Scaffolds for Bone Tissue Engineering” (Poster), Annual Meeting of Biomedical Engineering Society (BMES), 2010
  26. K. Sheets, S. Wunsch, A. Nain, G. Michalopoulos. “Directed Cellular Migration on STEP-Aligned Polymeric Micro/Nanofibers” (Poster), Annual Meeting of Biomedical Engineering Society (BMES), 2010
  27. K. Sheets, S. Wunsch, A. Nain, G. Michalopoulos. “Cellular Dynamics on Aligned Polymeric STEP Scaffolds:  Topological-Mechanistic Route to Tissue Engineering” (Poster), NC term, 2010
  28. K. Sheets, S. Wunsch, A. Nain.  “STEP enabled Ordered Polymeric Micro/Nanofiber Scaffolds for Studying Cellular Dynamics” (Presentation), Annual Meeting of the American Institute of Chemical Engineers (AIChE), 2010
  29. S. Wunsch, K. Sheets, and A.Nain. “Bridging The Spatial Dimensions: Cellular Dynamics Across Flat Films and Aligned 3D Polymeric Micro/Nanofibers” (Presentation and Published Abstract), ACC Interdisciplinary Forum, 2010
  30. M. Kargar, J. Wang, A. Nain and B. Behkam, Theoretical and Experimental Investigation of the effects of ordered polymeric nanofibers on wetting regimes, Paper 429a, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Salt Lake City, Utah, November 7-12, 2010
  31. Nain, STEP-enabled Polymeric Micro/Nanofiber Scaffolds for Tissue Engineering, Paper 352f, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Salt Lake City, Utah, November 7-12, 2010
  32. A. Nain, STEP enabled Isodiameteric Design Space for Ordered Deposition and Characterization of Polymeric Micro/Nanofiber Arrays, Paper 348h, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Salt Lake City, Utah, November 7-12, 2010
  33. A. Nain, STEP enabled ordered polymeric Micro/Nanofiber Scaffolds for Studying Cellular Dynamics, Paper 318c, Annual Meeting of the American Institute of Chemical Engineers (AIChE), Salt Lake City, Utah, November 7-12, 2010
  34. S. Bakhru, and A. S. Nain, STEP-Aligned Polymer Fiber Meshes Direct Migration and Neuronal Differentiation of Neural Stem Cells, OP-9-2-4A, Engineering New Frontiers in Medicine and Biology, Annual Meeting of Biomedical Engineering Society (BMES), Austin, Texas, October 6-9, 2010
  35. D. Ker, A. Nain, J. Suhan, B. Chu, L. Weiss, and P. Campbell, Spatial Control of Cell Differentiation Fate Using Oriented Sub-micron Fibers and Bioprinted Growth Factors, PS-8B-21-28, Engineering New Frontiers in Medicine and Biology, Annual Meeting of Biomedical Engineering Society (BMES), Austin, Texas, October 6-9, 2010.
  36. J. Wang, and A. S. Nain, Step Based Isodiametric Design Space for Aligned Deposition of Polymer Nanofibers in Multiple Layers, PS-8B-20-267, Engineering New Frontiers in Medicine and Biology, Annual Meeting of Biomedical Engineering Society (BMES), Austin, Texas, October 6-9, 2010
  37. A. S. Nain, and G. Michalopoulos, STEP enabled Long Term Culture of Hepatocytes on Cross-Hatch Pattern of Sub-micron Polymeric Fibers, PS-8B-7-116, Engineering New Frontiers in Medicine and Biology, Annual Meeting of Biomedical Engineering Society (BMES), Austin, Texas, October 6-9, 2010.
  38. M. Kargar, J. Wang, A. S. Nain, and B. Behkam, Nanofibrous Engineered Surfaces for Study of Bacterial Adhesion and Biofilm Formation, PS-7A-9-168, Engineering New Frontiers in Medicine and Biology, Annual Meeting of Biomedical Engineering Society, Austin, Texas, October 6-9, 2010.

Patents

  1. Methods, Apparatuses and Systems for Fabrication of Polymeric Nano- and Micro-fibers with controlled Diameter and Orientation, Pending. 
  2. Control of Cell Behavior by Aligned Micro/Nanofibrous Biomaterial Scaffolds Fabricated by Spinneret-Based Tunable Engineered Parameters (STEP) Technique, Pending.
  3. Methods, Apparatuses and Systems for Fabrication of Polymeric Nano- and Micro-Fibers in Aligned Configurations, Pending. 

Thesis

  • In Progress

 

To request a PDF version of any of these publications please contact Amrinder Nain.


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BMES 2012